Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion
Cell,
A large-scale single-cell transcriptomic and epigenomic atlas of Alzheimer’s disease (AD) dissects regulatory programs during…
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors
Cell,
Severe COVID-19 can reprogram hematopoiesis and establish epigenetic memory in hematopoietic stem and progenitor cells (HSPC…
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
Cell,
Analysis of primary prostate cancer and circulating tumor cells reveals how DNA hypomethylation during early prostate…
A transcription factor atlas of directed differentiation
Cell,
Generation of a comprehensive human transcription factor (TF) barcoded ORF library and further application to embryonic stem…