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https://t.co/4G45HT4Xnl "Importantly, while complete absence of MALT1 affects the differentiation of regulatory T (Treg) cells in vivo, the MALT1 protease inhibitor mepazine did not affect Treg development."
https://t.co/4G45HT4Xnl "Importantly, while complete absence of MALT1 affects the differentiation of regulatory T (Treg) cells in vivo, the MALT1 protease inhibitor mepazine did not affect Treg development."
https://t.co/4G45HT4Xnl "We demonstrate that administration of mepazine prophylactically or after disease onset, can attenuate EAE."
Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis https://t.co/4G45HT4Xnl