Oncolytic reovirus enhances the effect of CEA immunotherapy when combined with PD1-PDL1 inhibitor by reducing the immunosuppressive tumor microenvironment in a colorectal cancer model
Preprint in Research Square (February 2024)
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Reovirus infection of tumor cells reduces the expression of NKG2D ligands, leading to impaired NK-cell cytotoxicity and functionality
Article in Frontiers in Immunology (September 2023)
Pre-treatment of oncolytic reovirus improves tumor accumulation and intratumoral distribution of PEG-liposomes
Article in Journal of Controlled Release (January 2023)