@DGisselsson Thank you, David! We deliberately avoided trying to incorporate subclonal CNAs in Pairtree. (Quaid's group previously developed PhyloWGS, though, which does: https://t.co/rk0fevR9VS.) This decision was based on our participation in PCAWG.
1,041 followers
610 followers
RT @michaelhoffman: QM: Generative modeling solution: PhyloWGS. Pr(tree) Pr(f|tree) Pr(VAF|f,tree). Tree and parameter prior is tree-struct…
23,321 followers
QM: Generative modeling solution: PhyloWGS. Pr(tree) Pr(f|tree) Pr(VAF|f,tree). Tree and parameter prior is tree-structured stick breaking process. Likelihood binomial #probgen18 https://t.co/UPKfq0yVIR
3,862 followers